- No More Heroes: Desperate Struggle finally comes to Japan on October 21, 2010.
- On May 28, 2010 No More Heroes: Desperate Struggle comes to Europe.
- On January 26, 2010 the game is released on North America.
- On May 29, 2009, the newest trailer for No More Heroes: Desperate Struggle was shown prior to E3 2009.
- On October 9, 2008, the trailer for No More Heroes: Desperate Struggle, the sequel to No More Heroes, was shown at the Tokyo Game Show in Chiba, Japan.
- On March 20, 2008, No More Heroes was released in Australia.
- On March 17, 2008, No More Heroes Wiki was founded.
- On March 15, 2008, during an interview with Computer and Video Games, Goichi Suda revealed that beyond the Xbox 360 game in development by Grasshopper, he would be interested in producing No More Heroes 2 for the Wii, on the condition that the game sells enough to convince its publishers. He also revealed that a real-life anime adaption of Pure White Lover Bizarre Jelly would also possibly be produced in the future.
- On March 14, 2008, No More Heroes was released in Europe. A soundtrack featuring remixes of themes from the game and its original soundtrack was released on this date as well, entitled No More Heroes Sound Tracks: Dark Side.
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